Addiction is a primary, chronic disease of brainthat results when a person ingests a substance (e.g., alcohol, drugs, nicotine) or engages in an activity (e.g., gambling, sex, eating habit) that leads to characteristic psychological, social and spiritual manifestations. Addictions can be extremely pleasurable but the continued use/act of which becomes addictive and interferes with ordinary life responsibilities such as health, relationships or work. Like other chronicdiseases, it often involves cycles of relapse and remission. Without proper treatment or early engagement in recovery activities, it is progressive and can result in disability or even premature death.